INS and type 2 diabetes mellitus: Type 2 diabetes disease progression is marked by escalating therapies and deteriorating glycaemic control26 which may not respond to intensification of insulin regimens.15 Studies using professional continuous monitoring in insulin-treated type 2 diabetes have generally failed to report improvement in HbA1c.7,27,28 The clinically significant reduction in HbA1c documented in this study, without increasing hypoglycaemic exposure, is a key finding.