In colorectal cancer, linc00152 promotes the proliferation, migration, and invasion in the miR‐139‐5p/NOTCH 1 axis, while also inducing the resistance of colorectal cancer cells to 5‐fluorouracil‐mediated apoptosis.50, 51 Moreover, linc00152 can facilitate the epithelial‐to‐mesenchymal transition and metastasis in colon cancer by binding to cytoplasmic β‐catenin, thereby impeding casein kinase 1 (CK1)‐induced β‐catenin phosphorylation and enabling β‐catenin as well as linc00152 to be translocated into the nucleus in a positive feed‐forward circuit.52 Here, NOTCH1 is linked to colorectal cancer.