The serum MCP‐1 level of the FAIM‐overexpression group (LV‐FAIM) and PACAP‐injected group (PACAP) was dramatically declined compared with that in the obesity group (Obesity), while the serum MCP‐1 level of the FAIM‐knockdown group (LV‐shFAIM) rose continuously compared with that in the obesity group (Obesity) (Figure 5A). The gene discussed is CCL2; the disease is obesity due to melanocortin 4 receptor deficiency.