When we divided the group of AAb+ children into progressors and non-progressors to type 1 diabetes, we were interested to observe that the frequency of CXCR5−PD-1hi Tph cells was only increased in the children that later progressed to type 1 diabetes (Fig. 2h and ESM Fig. 2). The gene discussed is TPH1; the disease is type 1 diabetes mellitus.