NLRP3 and Corneal opacity: We employed alkali burn injury and application of lipopolysaccharide (LPS) to induce sterile inflammation of the cornea in wild-type mice and NLRP3 KO (knockout, Nlrp3−/−) mice, and investigated NLRP3-dependent corneal opacity, neutrophil infiltration, and up-regulation of proinflammatory molecules.