CCT7 and SSA1 were included in these analyses because they are part of the overrepresented gene ontology category of the CCT-complex, identified by both our study and Choy et al. Finally CCT7, SSE2, MRC1, RSM7, HSL7 and SSA1, all have identified human homologs (see discussion) which could make their further investigation more relevant to LOH events in cancers. The gene discussed is MRC1; the disease is cancer.