Apart from these conventional clinical risk factors, systematic reviews of genetic risk factors demonstrated that plasminogen activator inhibitor-1 (PAI-1) and FMS-related tyrosine kinase 1 (FLT1)—known to be linked with risks of coronary heart disease and heart failure—were also strongly associated with preeclampsia [45,46,47]. The gene discussed is SERPINE1; the disease is coronary artery disorder.