STAT3 and cancer: In addition to the above pathways, AURKA is known to be involved in many other pathways and form signaling networks in cancers, including tumor suppressor p53, tumor protein p73, mouse double minute 2 homolog (MDM2), Glycogen synthase kinase 3 beta (GSK3b), v-myc myelocytomatosis viral related oncogene (N-MYC), proto-oncogene tyrosine-protein kinase (SRC), signal transducer and activator of transcription 3 (STAT3), and breast cancer gene 1/2 (BRCA1/BRCA2) [49].