HMGB1 has been associated with diabetes or high glucose in several retinal cell types, including pericytes (Kim et al. 2016 [31]), endothelial cells (Liu, Jiang, and Steinle 2017 [17]), and glial cells and retinal ganglion cells (Santos et al. 2014 [32], Dvoriantchikova et al., 2011 [13]). The gene discussed is HMGB1; the disease is diabetes mellitus.