IFNγ‐priming of macrophages, which is crucial in restricting pathogen growth and controlling infection, upregulates key antimicrobial molecules that mediate cell‐intrinsic control of pathogens (Mosser & Edwards, 2008; MacMicking, 2012; Randow et al, 2013) and enhances pyroptotic cell death (Shenoy et al, 2012; Meunier et al, 2014; Pilla et al, 2014; Finethy et al, 2015; Santos et al, 2018). This evidence concerns the gene IFNG and infection.