EIF4G1 and Reduced sperm motility: After ruling out the mutations that show extremely low expression in the testis or that have low pathogenicity based on protein expression databases (https://www.proteinatlas.org) and bioinformatic analysis, we obtained biallelic mutations of EIF4G1 (RefSeq NM_004953.4, genome build GRCh37/hg19) because this gene was the only gene that was potentially closely associated with severe asthenozoospermia based on the previous literature.