IFN-γ−/− knockout mice succumbed to a low infection dose of PruΔgra12 parasites, with kinetics similar to those in IFN-γ−/− mice infected by parental type II PruΔku80 parasites (Fig. 5A), suggesting that IFN-γ was required to control PruΔgra12 infection. Here, IFNG is linked to infection.