Together, these results indicate that TET1 expression is high, while TET2 is low in T-ALL derived from EμSRα-tTAα;tet-o-MYC and in human Burkitt lymphoma, revealing a direct correlation between MYC and TET1, and an inverse correlation between MYC and TET2 expression levels. Here, TET2 is linked to acute lymphoblastic leukemia.