To determine the overlap between TET1, TET2, and MYC target genes in T-ALL, we used the DEGs upon TET1 KD and ectopic expression of TET2 in human T-ALL cells (CCRF-CEM) and compared them with previously identified MYC target genes [35–37] (Fig. 8). Here, TET2 is linked to acute lymphoblastic leukemia.