To determine the effect ectopic TET2 expression has on DNA (hydroxy)methylation and RNA expression in human T-ALL cells, we carried out MeDIP-, hMeDIP-, and RNA-seq analysis, comparing CCRF-CEM cells before (EV) and upon ectopic expression of TET2 using cDNA (TET2) (Fig. 7). This evidence concerns the gene TET2 and acute lymphoblastic leukemia.