RT-qPCR analysis for MYC and its canonical target gene, Ornithine Decarboxylase 1 (ODC1), verified MYC inactivation (96.17-fold, P = 8.41 × 10−9, and 12.36-fold, P = 1.2 × 10−5 lower on day 3, respectively) in EμSRα-tTAα;tet-o-MYC-derived T-ALL cells (Fig. 2a). The gene discussed is ODC1; the disease is acute lymphoblastic leukemia.