Recently, Wang et al. (2014) reported DMD deletions in 25 of 40 myogenic tumors (29 gastrointestinal tumors (GIST), 4 rhabdomyosarcomas, and 7 leiomyosarcomas (LMS)), and observed that forced re-expression of the miniDMD construct (lacking exons 17–48) inhibited cell migration, cell invasion, anchorage independence, and invadopodia formation [3]. Here, DMD is linked to rhabdomyosarcoma.