AGER and nephritis: To that end we injected pristane into WT and RAGE−/− animals and determined development of serum anti-dsDNA antibody levels and nephritis five months (replicate 1: n = 6 RAGE−/− and 7 WT mice), six months (replicate 2: n = 6 RAGE−/− and 8 WT mice) and seven months (replicate 3: n = 15 RAGE−/− and 10 WT mice) later.