Besides, the rate of male patients carrying A allele was significantly higher compared with the female patients.13 On the contrary, Li and his team have performed a study of HT patients in China and have found that 2 SEPS1 SNPs (rs2009895‐rs28665122) were significantly associated with female HT, but not in male population,14 confirming the propulsive role of this gene in chronic inflammation. The gene discussed is SELENOS; the disease is hematocrit.