HIF-1α in the Pa-Tu-8988S and Pa-Tu-8988T pancreatic cancer cell lines have also been shown to suppress the expression of the UDP-glucuronosyltransferase (Kato et al., 2016), cytosolic O-GlcNAc transferase (OGT) (Liu et al., 2014) and glucosylceramide synthase (GCS) (Zhao et al., 2003). Here, UGCG is linked to pancreatic neoplasm.