IDH1 and glioma: Subsequently, the German National Cancer Center launched a Phase I trial, IDH1 Peptide Vaccine in IDH1 R132H Mutant III-IV Glioma (NOA-16) (NCT02454634) (36), and Duke University also launched a clinical trial, called “IDH1 Peptide Vaccine for Recurrent Grade II Glioma (RESIST)” (NCT02193347) (37).