ABPA: allergic bronchopulmonary aspergillosis; Af: Aspergillus fumigatus; CB: central bronchiectasis; CF: cystic fibrosis; IgE: immunoglobulin E; IgG: immunoglobulin G; ISHAM: International Society for Human and Animal Mycology. The gene discussed is IGHE; the disease is allergic bronchopulmonary aspergillosis.