Mechanistically, recombinant TGFβ1 induced LINC01614 expression, while pharmacological inhibition of TGFβ signaling (using SB-431542) and FAK (using PF-573228) inhibited LINC01614 expression in BC cells (Fig. 6e), thus implication TGFβ and FAK signaling in regulating LINC01614 expression in BC cells. The gene discussed is PTK2; the disease is breast cancer.