Figure 4 shows the effect of the Glu transporter inhibitors TBHA (nonspecific inhibitor of transporters including glutamate aspartate transporter [GLAST]) and DHK (specific inhibitor of glutamate transporter 1 [GLT-1]) on the amelioration of TD-induced decreased Glu uptake by YKS (100 μg/mL) and YKSCH (140 μg/mL). Here, SLC1A2 is linked to thanatophoric dysplasia.