The following pathways had the largest number of genes involved: Platelet activation (11, 35.5%), Rap1 signaling pathway (12, 38.7%), Focal adhesion (9, 29.0%), Proteoglycans in cancer (8, 25.8%), PI3K-Akt signaling pathway (7, 22.6%), and Pathways in cancer (7, 22.6%). The gene discussed is PIK3CD; the disease is cancer.