TRPM8 and Ehlers-Danlos syndrome: In addition, a more complete understanding of this antiepileptic effect requires further studies: the expression of TRPM8 channels in the somatosensory cortex, the effects of TRPM8 inactivation under cooling conditions on EDs, the effects of TRPM8 activation on sensorimotor functions, and the effects of TRPM8 activation in chronic phase on EDs using TRPM8KO mice.