Moreover, the expression and function of Kv3.3 channels are altered in CHO cells transfected with mutated SCA13 as well as mRNA expression of Kv3.3 in animal with cerebellar ataxia (Herman-Bert et al., 2000; Waters et al., 2005, 2006; Zhao et al., 2013); Table 3). The gene discussed is KCNC3; the disease is cerebellar ataxia.