After treatment with lentivirus-mediated siRNA, the mean tumor volumes of the mice were measured, and in the blank control group, negative group (N-siRNA), and BTF3-siRNA group they were 143.38 ± 59.70 mm3, 72.60 ± 47.33 mm3, and 4.66 ± 8.25 mm3, respectively, with statistically significant differences between BTF3-siRNA and NC-siRNA groups (Fig. 4b). The gene discussed is BTF3; the disease is neoplasm.