To examine potential relationships between c-SRC activity, mTORC1 activation and PRC2 expression in human breast cancer, we analyzed a tissue microarray (TMA) series containing primary samples from a cohort of 292 patients, revealing that markers of SFK and mTORC1 activation correlate positively with each other and with EZH2 protein levels (Fig. 4a, b). This evidence concerns the gene EZH2 and breast cancer.