EZH2 and breast carcinoma: To examine potential relationships between c-SRC activity, mTORC1 activation and PRC2 expression in human breast cancer, we analyzed a tissue microarray (TMA) series containing primary samples from a cohort of 292 patients, revealing that markers of SFK and mTORC1 activation correlate positively with each other and with EZH2 protein levels (Fig. 4a, b).