IL1B and infection: Likewise, brain tissues of animals with S. epidermidis-infected catheters had higher levels of IL-10 (P < 0.001), IL-1β (P < 0.001), CCL2 (P < 0.001), and CCL3 (P < 0.001) at day 1 postinfection, demonstrating that the CSF inflammatory milieu mirrors that of the brain tissue during early infection.