ICAM1 and acute myeloid leukemia: We identified AML cell lines, which expressed low levels of ICAM-1, as relatively insensitive to CVA21-induced direct oncolysis (see Additional file 3: Figure S2A and B, respectively), and MM cell lines (except OPM2), which expressed higher levels of ICAM-1, as highly susceptible to CVA21 oncolysis (see Additional file 3: Figure S2C and D, respectively).