Neither levels of the apoptotic markers, cleaved poly (ADP-ribose) polymerase (PARP) and active caspase 3, nor the level of the autophagic marker, LC3-II, were changed in NSCLC cells after a 24-h treatment with BEZ235; the only exception was an increase in LC3-II in A549 cells (Additional file 1: Figure S4a). The gene discussed is CASP3; the disease is non-small cell lung carcinoma.