Among women with PCOS, there were negative correlations between % appendicular skeletal muscle mass and the homeostasis model assessment insulin resistance index (r = − 0.409; p < 0.01), high sensitivity C-reactive protein (r = − 0.608; p < 0.0001) and glycosylated hemoglobin (r = − 0.430; p < 0.0001). Here, CRP is linked to Insulin resistance.