The major whey proteins, namely α-lactalbumin, β-lactoglobulin and bovine serum albumin, do not have immunomodulatory functionalities that can directly be linked to the allergy-protective effects of raw cow’s milk, but several less abundant whey proteins such as immunoglobulins, lactoferrin, TGF-β and IL-10 theoretically do [24,25,26]. This evidence concerns the gene LTF and allergic disease.