Molecular analysis revealed that NFBTA significantly up-regulated genes, including FOS, RAF1, BRAF, NFKB1, NFKB1A, NFKB2, PIK3CA, PTEN, and TP53. Recently, various investigations have established that changes in gene expressions are directly associated with cancer, as well as the prevention of cancer. This evidence concerns the gene PIK3CA and cancer.