A flavonoid of the flavanone class, HLBT-100 (or HLBT-001), isolated from Tillandsia recurvata exhibited potent anti-prostate cancer (IC50 values < 0.100 μM), affecting the cell cycle, activate caspase-3/7, cause DNA fragmentation culminating in apoptotic cell death. The gene discussed is CASP3; the disease is prostate cancer.