INS and GM2 gangliosidosis: Other important pathways downstream to miR-29a include the Insulin/IGF pathway, the protein kinase MAP kinase signaling cascade, Phosphoinositide 3-kinases (PI3 kinase) pathway, neurotransmitters pathway and Integrin signaling pathway that, as reported above, might be correlated with biological processes altered in GM2 gangliosidosis.