In terms of molecular mechanisms underlying chemotherapy resistance, they revealed that CD117 overexpression induces the upregulation of ATP-binding cassette G2 (ABCG2) through the Wnt/β-catenin signaling pathway, thereby enhancing the chemotherapy resistance of ovarian cancer cells in a hypoxic tumor microenvironment [42]. The gene discussed is ABCG2; the disease is ovarian carcinoma.