Although the luminal-papillary subtype of UCB is characterized by FGFR3 mutations and it was reported that the majority of UTUC in the non-endemic area also resembled this subtype of UCB [119], FGFR3 mutations were noted in only 0–8% of AA-associated UC [10,90,116]. This evidence concerns the gene FGFR3 and renal pelvis/ureter urothelial carcinoma.