LACTB and infection: Ampicillin–sulbactam is indicated for the treatment of skin and skin structure infections caused by beta-lactamase-producing S. aureus, E. coli, Klebsiella spp., P. mirabilis, Bacteroides fragilis, Enterobacter spp., and Acinetobacter baumannii–calcoaceticus complex; intra-abdominal infections caused by beta-lactamase-producing E. coli, Klebsiella spp., Bacteroides spp., and Enterobacter spp.; and gynecological infections caused by beta-lactamase-producing E. coli and Bacteroides spp.