The pathogenesis of SJS is unknown, but it appears to involve cell–mediated keratinocyte apoptosis via the Fas signaling cascade and granular release.[6] SJS can be caused by exposure to certain medications, infection or malignancy.[7] Ocular manifestations of SJS can be categorized into acute stage, including conjunctivitis and meibomitis, and chronic stage including meibomian gland dysfunction (MGD) and ocular surface keratinization.[8]. This evidence concerns the gene FAS and Schwartz-Jampel syndrome.