Firstly, they did not separate STS from bone sarcoma, which represents a different group of sarcomas; Secondly, they combined both multivariate Cox hazard regression analysis data and univariate analysis data together, thus could not assess the independent role of CRP as a prognostic factor; Thirdly, they did not consider DSS as an endpoint, which might be more reliable than OS when it comes to sarcoma-caused death. This evidence concerns the gene CRP and bone sarcoma.