GPT and liver disorder: Although the effect size was imprecisely estimated, clear evidence showed that blood markers for liver disease improved, including ALT (–9.81 U/L; 95% CI, –13.12 to –6.50; I2 = 97%; to convert to microkatal per liter, multiply by 0.0167) (Figure 2) and AST (–4.84 U/L; 95% CI, –7.31 to –2.38; I2 = 96%; to convert to microkatal per liter, multiply by 0.0167) (eFigure 1.5 in the Supplement).