Upregulation of EphrinB2, CXCR4, DLL4, HEY, Jagged, Notch1, and Notch4 gene expressionNICD protein expressionAc-LDL uptakeIn vitro and in vivo angiogenesisAlignment response to shear stressImproved cardiac function in myocardial infarction mouse model. The gene discussed is NOTCH1; the disease is myocardial infarction.