The important tumor-associated pathways were antigen presentation pathway (Supplementary Figure 1 item 1; Table 1), mitochondrial dysfunction (Supplementary Figure 1 item 2; Table 1), GP6 signaling pathway (Supplementary Figure 1 item 3; Table 1), EIF2 signaling (Supplementary Figure 1 item 4; Table 1), and glutathione-mediated detoxification (Supplementary Figure 1 item 5; Table 1). The gene discussed is EIF2S2; the disease is neoplasm.