IL1B and periodontitis: Present study showed that IL-1β level were raised in the saliva of naswar users as compared to the healthy controls.IL-1β levels in both GCF and saliva of other type of STP users, was also found to be raised; emphasizing the point that IL-1β plays a critical role in periodontitis and that its levels were increased more when associated with a risk factor such as use of STPs.14,19,20 This could be due to the fact that naswar users have a poorer periodontal condition as shown by elevated PD and CAL.