TNF and multiple sclerosis: For instance, lnc‐THRIL is upregulated in multiple sclerosis patients compared with healthy controls.15 And lnc‐THRIL is clearly lower in the acute phase compared with convalescent‐phase in patients with Kawasaki disease.9 The close association of lnc‐THRIL with Kawasaki disease and multiple sclerosis as well as its correlation with TNF‐α implicate that it may be involved in other inflammatory diseases, while it is not studied in sepsis yet.