FASLG and autoimmune polyendocrinopathy: In a meta-analysis of 11 studies including 1218 patients with APS, 318 patients with SLE, 49 asymptomatic aPL-positive individuals and 1859 healthy controls, Radin et al. [16] reported that 45.4% of patients with APS were positive for anti-DI and that four of the five studies that looked at association between anti-DI-positivity and risk of thrombosis found such an association, with odds ratios ranging between 2.5 and 4.