Since MYC and MAX co-occupy the LCL MTHFD2 promoter (Figure 2F) and given MYC’s role in MTHFD2 regulation in acute myelogenous leukemia (Pikman et al., 2016), we investigated a potential role for MYC in EBV induction of MTHFD2 expression. This evidence concerns the gene MAX and acute myeloid leukemia.