That study reported that anti‐Ascaris IgE was associated with an increased risk of ever having asthma among 5–year old children.18 Nakazawa et al29 reported that Ascaris lumbricoides antigens induced the production of antibodies crossreactive to mite antigens from Dermatophagoides farina, indicating that mast cell‐bound anti‐Ascaris IgE on the airway surface produced in the infected individual might crossreact with the inhaled Dermatophagoides antigen present in the environment. This evidence concerns the gene IGHE and asthma.