DDIT3 and hereditary sensory and autonomic neuropathy: We also found that GW administration reversed the activated ERS in CIP mice, measured by the enhanced expression of ERS markers, C/EBP homologous protein (CHOP), and activating transcription factor 4 (ATF4) in ACC (Additional file 7: Figure S6) by qPCR, indicating that LXR activation attenuated ERS in CIP.