It is important to note that CD8+ cells that coexpress CD16 markers correspond to a subpopulation of cytotoxic T cells that display low CD8 expression, frequently called CD8low; however, CD56 expression on CD8+ cells from TB patients is not limited to CD8low, as there is also a CD8high fraction which expresses CD56 (Figure 2f,h). This evidence concerns the gene NCAM1 and tuberculosis.