CD8A and tuberculosis: In fact, mycobacterial antigen (Ag)‐specific CD8+ T cells are important in measuring the protective capacity of new TB vaccines in clinical trials.8, 10, 11, 12 Likewise, some immunogenic peptide antigens have been proposed as immunotherapy candidates for inducing cytotoxic activity in TB drug‐resistant patients.13 Thus, it has now been accepted that CD8+ T cells play a critical role in the immune response against Mtb infection, as reviewed by Lin and Flynn.14