TB patients, compared with healthy controls, have increased serum levels of TNF (median healthy controls 1 IQR 0.2–10 vs. TB patients 8 IQR 2–177 pg/ml, p = 0.02), IL‐8 (median healthy controls 1 IQR 0.1–6 vs. TB patients 8 IQR 2–18 pg/ml, p = 0.0001), and IL‐4 (median healthy controls 0.4 IQR 0.07–3 vs. TB patients 2 IQR 0.5–pug/ml, p = 0.002; Figure 5b,d,e, respectively). This evidence concerns the gene TNF and tuberculosis.