CD8A and tuberculosis: Regarding the coexpression of CD25 on CD8, our data show that the frequency of CD8+CD25+ cells was practically absent without a stimulus (median healthy controls 2% IQR 1–7 vs. 2% IQR 0.5–4 in TB patients; Figure 3d); in accordance with previous reports, the percentage of CD8+CD25+ cells was still low in the first hours following polyclonal stimulus (median healthy controls 2% IQR 1–4 vs. 2% IQR 1–5 in TB patients; Figure 3d).