CD8A and tuberculosis: Our data show that CD8+ T cells from TB patients had a higher level of cytotoxic activity using 20 μg of CFAE (median healthy control, 19% vs. TB patients, 40%, p = 0.005); however, the healthy group required 40 μg of CFAE to produce the maximum level of cytotoxic function (median healthy control, 28% vs. TB patients, 21.5%).