NLRP3 and Parkinson disease: The decreased expression of miR-7 is able to increase the expression of alpha-synuclein25, and at the same time it may lead in a defective control over NLRP3 inflammasome activation in PD; it is tempting to speculate that the augmented amounts of miR-223-3p we observed in these patients could be an attempt to balance such excessive chronic activation.